How does your brain work?
You have noticed that it is a task that we can do well, even though we have to store the relevant information (location) “in mind” during a delay period in order to be able to perform correctly. If during that period your brain had been scanned to obtain functional magnetic resonance images in order to indentify the cerebral areas that were consuming more oxygen during the delay period, you would have seen something similar to this image.
Some areas in the frontal and parietal cortices activate selectively when we maintain information in working memory.
This has also been observed at the neuronal level in the brain of monkeys that perform these tasks. Some neurons in these areas show elevated activity (rhythm of emission of action potentials) during the delay period in response to some property of the stimulus to be memorized (in the previous task, location).
This evidence led to the formulation of a theoretical framework to explain these observations in the operation of a network of biological neurons.